The System Graph leverages state of the art LLMs, advanced graph technology, complexity science, and causal inference techniques to generate a systems model of the world — unifying scales and domains to connect siloed knowledge.
Modeled as one complex system, unifying scales (e.g. molecular, epidemiological) and domains (e.g. health, climate)
Based on empirical quantitative findings extracted from scientific papers and expert-curated databases using SOTA large language models
Extracted findings are linked and normalized in a large-scale graph via a patented compound AI system with causal inference techniques
Connects previously siloed knowledge and meta-analyzes and synthesizes research
Interpretable and transparent with complete knowledge provenance
Continuously ‘trained’; no knowledge cut-off
Primary nodes are variables that are interoperable with established ontologies (e.g. UMLS, Wikidata)
Accessible and queryable via GraphQL, REST APIs, or natural language
Using AI, the System Graph extracts, grounds, and links findings from verified sources like peer-reviewed studies and expert-curated databases.
Integrating Retraction Watch Database with System Graph
Using AI, the System Graph extracts, grounds, and links findings from verified sources like peer-reviewed studies and expert-curated databases.
This generates millions of rich, quantitative relationships that cut across sources and fields.
Those quantitative relationships are joined with mechanistic relationships to link scales of knowledge.
Statistical
Adjusted hazard ratio
Adjusted odds ratio
Coefficient of determination
Elasticity
Gini coefficient
Hazard ratio
Incident rate ratio
Mean difference standardized
Mean difference unstandardized
Odds ratio
Pearson correlation coefficient
Prevalence ratio
Regression coefficient
Relative risk ratio
Risk difference
Spearman correlation coefficient
T-test
Mechanistic
Acetylation
Activation
Complex
Conversion
Deacetylation
Decrease amount
Defarnesylation
Degeranylgeranylation
Deglycosylation
Dehydroxylation
Demethylation
Demyristoylation
Depalmitoylation
Dephosphorylation
Deribosylation
Desumoylation
Deubiquitination
Farnesylation
Geranylgeranylation
Glycosylation
Hydroxylation
Increase amount
Inhibition
Methylation
Modification
Myristoylation
Palmitoylation
Phosphorylation
Ribosylation
Sumoylation
Translocation
Ubiquitination
Integrating the EMBL GWAS Database into the System Graph
Integrated sources
224 added today
No change
224 added today
No change
3 added today
No change
Surfaced by the System Graph and extracted from verified sources including peer-reviewed studies and expert-curated databases
Interpretable and transparent with complete knowledge provenance
Primary nodes are variables that are interoperable with established ontologies
Accessible and queryable via GraphQL, REST APIs, or natural language
Classifying Study Type Using Deep Learning