System API

Knowledge infrastructure for research and development

Whether you're training a model, building a research tool, enhancing your application's intelligence, or powering advanced analytics, our API is designed to give you the full power of the System Graph.

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Comprehensive coverage

The API gives you access to a wide array of data sources that are integrated into a cohesive graph. See our corpus of source material here.

Always up to date

The System Graph is updated daily, ensuring that data lag isn’t an issue. Your applications and models will always be using the most up-to-date data.

Scalable and reliable

The API is built on a scalable architecture that can handle high volumes of requests while maintaining reliability and performance.

Graph traversal

Case Study

How the Novartis Foundation uncovered the system of cardiovascular disease

Identify the risk factors, interventions, and outcomes for any disease

Explore potential multi-hop pathways

Interrogate a systems-level view of any disease

# Python SDK
topics = topics_api.search_topic_by_name(
topic_name="string"
) 

topic_id = topics[0].id
topics_api.get_topic_determinants(topic_id) 

{
 	"num_findings": int,
 	"num_studies": int,
 	"num_significant_findings": int,
 	"median_effect_size": float,
 	"last_updated": datetime.datetime(date),
 	"has_experimental_trial": bool,
 	"topic":{
  	"name": str, 		
    "umls_cuis": List[str],            
    "category": {TopicCategory}, 		      
    "roles": List[TopicRole]
    } 
}

{ 	
  "source": “string”, 
  "direction": “string”, 	
  "degrees": int, 
  "relationships": { 		  
    1: [ 			  
      "string", 		  
    ], 		  
    2: [ 			  
      "string", 		  
    ], 
  }, 
}

{   
  "directed": bool, 
  "multigraph": bool, 
  "nodes": [ 
    { 
      "id": "string", 
      "label": "string", 
      "category": "string", 
      "roles": [ 
        "string" 
      ] 
    } 
  ], 
  "links": [ 
    { 
      "source": "string", 
      "target": "string", 
      "last_published": ISO 8601 Timestamp, 
      "median_effect_size": float, 
      "num_studies": int, 
      "highest_cited": int, 
      "num_significant_findings": int, 
      "num_findings": int 
    } 
  ] 
}

Case Study

How the Novartis Foundation uncovered the system of cardiovascular disease

Evidence synthesis

Generates an accurate, comprehensive, transparent, and up-to-date research synthesis, powered by the System Graph and advanced GraphRAG techniques.

{
    "summaries": [
        {
            "synthesis_query": "string",
            "theme": "string",
            "summary": "string"
        },
        {
            "theme": "string",
            "summary": "string"
        }
    ]
}

Research findings

Retrieve all of the structured findings and metadata contained in the System Graph for a study or set of studies.

Research

System vs GPT-4: A More Accurate and Comprehensive Research Assistant

Research

Keeping Pace with Biomedical Breakthroughs: The Daily Influx of New Research Insights

{
    "study": {
        "id": "string",
        "doi": "string",
        "title": "string",
        "authors": [
            {
                "full_name": "string",
                "orcid": "string",
                "openalex_id": "string"
                ...
            }
        ],
        "journal": "string",
        "publish_date": "ISO 8601 Timestamp",
        "population": "string",
        ...
    },
    "id": "string",
    "finding_type": "string",
    "summary": "string": {
        "id": "string",
        "name": "string",
        ...
    },
    "variable_2": {
        "id": "string",
        "name": "string",
        ...
    },
    "statistic_type": "string",
    "statistic_value": int,
    "effect_size": int,
    "ci_upper": int,
    "ci_lower": int,
    "p_value": bool
}

Research

System vs GPT-4: A More Accurate and Comprehensive Research Assistant

Research

Keeping Pace with Biomedical Breakthroughs: The Daily Influx of New Research Insights

Build your own apps and models with the System API

Schedule a demo

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System API

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System API

Knowledge infrastructure for research and development

Graph traversal

Evidence synthesis

Research findings

Build your own apps and models with the System API